Straight gasoline will almost always give a 10-12% increase in MPG. Alcohol, while having a higher octane rating, burns "colder" if you will. It's approx. 60% the efficiency of gasoline, IIRC. Driving a '95 Impala SS from San Diego to Chicago last fall, we were running something around 18 or 19 mpg on the highway (decent clip if I may add, we probably could have gotten in the 20's had we been cruising a little slower) everywhere we bought straight gasonline. When we got into IL, with our wonderfull E10 (10% ethanol) we saw an immediate drop in mileage to 15-16. Now, it doesnt sound like much, but factor it in over the long haul and it's a lot. I've only noticed about a 10 mile difference per tank using gas here that's E10 vs straight gas, but it would add up realistically. And it is hard to notice moreso because I can suck a tank dry in a few hours, or I can ride all week, depending on if I'm just runnign back and forth to work or my girls, or if it's saturday night and I'm out looking for some fun/trouble. If you can buy straight fuel in your area in the octane rating you are looking for, I highly reccommend it, as you will notice better mileage over some time.