I agree with Richie -- 'way back when in 1975 I bought my first big bike -- a Daytona Orange BMW R90S. What a great bike (for the time). It cost me a year's pay.
To take care of my baby, I immediately started using Mobil 1 oil, the first full-synthetic oil commonly available. $5.00 a quart, as I recall, and back then $5.00 was not a trivial amount of money (not when $5,000 was a year's salary).
What a disaster. The bike _never_ broke in properly, even though I put 25,000 miles on it before I finally (and now, regretfully) sold it.
Moral of the story: Break it in well, _then_ go synthetic.