I agree with alot of the statements above. It's all in the rider and their discipline. #1 respect motorcycles. #2 have no fear. #3 know your limits. #4 be cool calm and relaxed.
I went to a Hayabusa very quickly. I started with very old bikes. 83 Seca 750 (1.5 years) 85 Ninja 900 (1 month) 86 GPZ1000 (2 weeks) then the Busa. 8 years later and 4 Busa's in, I'll never switch to anything but.
It's all in your wrist, but the biggest challenge is the weight of the bike. The Hayabusa is very comfortable once you're moving, so you'll find riding it is a breeze, manoeuvring it from a dead standstill, tip over, backing up and man handling is a challenge.
But make sure your head is on straight before you go for a machine like this. Respect it, and she'll love you!