Extended swingarms are centered, including those with extensions. If not, there is something wrong.
That being said, fat tire kits (usually 240mm) do generally offset the wheel to the right so the chain won't hit the tire's added width. There are ways around this but to keep the kits cheap, they generally ignore this offset. I think the offset is 1/4" to 1/2" or so.
Larger kits (300mm+) use jack shafts (added sprockets and chains) to move the drive mechanism out far enough to clear the fat tire. Another method is to use an offset sprocket style kit which doesn't require the jackshaft, but does require a sprocket cover that can support the new offset sprocket in the front.
Hope that helps somewhat.