Try in advance to book hotel room for every 400 to 700 miles. Anything longer than that and you're probably going to be riding past sunset and that's not a lot of fun. Also, by reserving room ahead of time, you don't pull into a hotel dead-tired only to find out that some convention is in town and all the hotels for 100 miles are booked and you've got to hit the road again.
Like it was said above, take your time, get off the bike after an hour and a half or two of riding, get some water, take a break.
Bring something to clean your face shield, ala Honda spray wax and a few paper towels. Bugs can make it hard to see after awhile. Also some chain lube.
I also carry a kryptonite cable and lock as well as a bike cover for theft reasons, especially if you're staying at hotels. If bike is covered, less likely thieves will take it if they don't know what you have and it's a pain to steal if locked up.
I also like ear plugs, as I'm less tired at the end of the day, if I don't have to deal with the wind noise. Don't forget your rain-suit, hate to do long distance without rain-gear. Get some gore-tex mits at REI or someother outdoor gear shop. Nothing more miserable than wet and cold hands if you're riding long distance.
Lastly, this time of year, you probably won't need it, but I've always taken an electric vest on really long trips or trips in the mountains. Weather changes real quick up there and can get pretty cold, even in summer. A vest can turn a miserable trip into a tolerable one. This is also true if you have to ride long distances in the rain. You can get chilled easily if the temps are in the low 70's or 60's and you do 300 plus miles in the rain.
Take a cell phone with you in case you break down. At least you won't have to walk miles from your bike to get help or a tow.
Just my $.02, have fun and be safe.