My wife follows me on a Kawi Z750S. Even though my wife has been riding for years, yes it is a bit more nerve racking when she's riding because I find myself looking out for both of us at the same time.
To hopefully lessen the odds of her going down I've tried to at least stack the odds in our favor.
Since most motorcycle accidents happen from the front, I always take the lead so hopefully she'll have time to react if a dumb cager pulls out in front of me. And as you know cagers love to tailgate or run up on the a## of bikes, so I installed Hyper-lights (with flashing option) on the rear of our bikes so they are a bit more visible.
And since we live in amongst a nightmare of traffic, I select backroads and less traveled roads to ride on, and steer clear of Interstates and such.
I'd hate to see her (or myself) go down, but hey, we're all playing the odds, and hoping for the best!