The Busa is okay to ride all day on, but not the same as a dedicated tourer such as the Kawasaki Concourse. I friend and I just came back from a 2300 km trip together. I was sore, he wasn't. I had to fill up every 230-250 km (and needed the stretch every 200). He didn't have to fill up until 400 or so km (so only about every other pit stop for him). We spent most of our time on the backroad twisties and I would need a break every 30 to 60 minutes from fatigue. He didn't.
The Connie has lots of torque, and he didn't have to try very hard to keep up with me on the straights (although I wasn't trying to lose him). He was able to hold his own in the corners, but that's where the Busa's sportbike configuration definitely showed its advantage, and why I am willing to put up with the sportbike-type ergos: it handles very well for my style of riding.
It's not as nimble as a dedicated sportbike due to it's weight, but I found it handles very well nonetheless (especially after I had the back raised 1" to increase the head angle -- make the angle of the forks steeper).
I've had a few bikes so far, and it's definitely my favourite. It's size and power will allow it to tour. It's sportbike configuration will allow it to carve corners quite well, but places your weight on your hands, wrists and arms. The handle bars can be raised with Heli-bars or a Genmar riser and that will help increase the comfort on the arms and wrists (but in no way is it as comfortable as sitting upright on a touring bike). For me, it's a good compromise.
Here's a vid of me on the Busa at Deals Gap: